ID AMPDB_400 PN Cystatin-11 PF Cystatin-11 GN CST11 CST8L SO Homo sapiens (Human) PL 138 PE Evidence at protein level XX AC 'A': 8, 'R': 5, 'N': 6, 'D': 6, 'C': 4, 'Q': 12, 'E': 10, 'G': 0, 'H': 5, 'I': 4, AC 'L': 15, 'K': 10, 'M': 5, 'F': 7, 'P': 5, 'S': 7, 'T': 8, 'W': 4, 'Y': 6, 'V': 11 AF 'A': 5.8%, 'R': 3.62%, 'N': 4.35%, 'D': 4.35%, 'C': 2.9%, 'Q': 8.7%, 'E': 7.25%, 'G': 0%, 'H': 3.62%, 'I': 2.9%, AF 'L': 10.87%, 'K': 7.25%, 'M': 3.62%, 'F': 5.07%, 'P': 3.62%, 'S': 5.07%, 'T': 5.8%, 'W': 2.9%, 'Y': 4.35%, 'V': 7.97% MA G MO L LO C, I, W BA 59 LA 79 AA 20 BC 16 MC 0 MF 0 XX MM 16506.03 AI 82.609 II 38.942 HP -0.38 HM 0.704 IP 7.027 C7 -0.783 SF 0.341, 0.13, 0.275 [Helix, Turn, Sheet] AR 0.123 ME 30940, 31190 XX TO Gram Negative Bacteria AM Antibiotic AM Antimicrobial AM Anti-gram-negative EA Not found IE Protease inhibitor IE Thiol protease inhibitor OE Enzyme inhibitor OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 12072414 XR PubMed: 11780052 XR PubMed: 15489334 XR UniProt: Q9H112 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q9H112 XR GemBank;EMBL: AF335480 XR GemBank;EMBL: AF335481 XR GemBank;EMBL: AL096677 XR GemBank;EMBL: CH471133 XR GemBank;EMBL: BC121079 XR GemBank;EMBL: BC121080 XR CCDS: CCDS13154.1[Q9H112-2] XR CCDS: CCDS13155.1[Q9H112-1] XR RefSeq: NP_543020.2[Q9H112-2] XR RefSeq: NP_570612.1[Q9H112-1] XR STRING: 9606.ENSP00000366208 XR IntAct: XR MINT: XR DIP: XR BioGRID: 126748 XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR042930 XR InterPro: IPR000010 XR InterPro: IPR046350 XR PANTHER: PTHR47886 XR PROSITE: XR Ensembl: ENSGT00910000144356 XR KEGG: hsa:140880 XR GeneTree: ENSGT00910000144356 XR BRENDA: XR BioCyc: XR RNAct: Q9H112 SQ SEQUENCE 16506.03 DA MW 138AA MMAEPWQALQ LLLAILLTLM ALPYQARKKT FLSVHEVMAV ENYAKDSLQW ITDQYNKESD DKYHFRIFRV LKVQRQVTDH LEYHLNVEMQ WTTCQKPETT NCVPQERELH KQVNCFFSVF AVPWFEQYKI LNKSCSSD // ID AMPDB_1071 PN Cystatin-9 PF Cystatin-9 GN Cst9 Cresp SO Mus musculus (Mouse) PL 137 PE Evidence at transcript level XX AC 'A': 4, 'R': 8, 'N': 7, 'D': 2, 'C': 5, 'Q': 4, 'E': 9, 'G': 2, 'H': 4, 'I': 6, AC 'L': 15, 'K': 9, 'M': 5, 'F': 11, 'P': 7, 'S': 12, 'T': 12, 'W': 2, 'Y': 4, 'V': 9 AF 'A': 2.92%, 'R': 5.84%, 'N': 5.11%, 'D': 1.46%, 'C': 3.65%, 'Q': 2.92%, 'E': 6.57%, 'G': 1.46%, 'H': 2.92%, 'I': 4.38%, AF 'L': 10.95%, 'K': 6.57%, 'M': 3.65%, 'F': 8.03%, 'P': 5.11%, 'S': 8.76%, 'T': 8.76%, 'W': 1.46%, 'Y': 2.92%, 'V': 6.57% MA MO L LO D, G, W BA 61 LA 76 AA 21 BC 11 MC 0 MF 0 XX MM 16093.819 AI 81.752 II 54.962 HP -0.118 HM 0.642 IP 9.308 C7 6.063 SF 0.343, 0.204, 0.241 [Helix, Turn, Sheet] AR 0.124 ME 16960, 17210 XX TO Francisella tularensis (Gram-negative) AM Antimicrobial AM Anti-gram-negative EA Not found IE Protease inhibitor IE Thiol protease inhibitor OE Enzyme inhibitor OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 9826679 XR PubMed: 16141072 XR PubMed: 19468303 XR PubMed: 15489334 XR PubMed: 15923608 XR PubMed: 23922243 XR UniProt: Q9Z0H6 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q9Z0H6 XR GemBank;EMBL: Y18243 XR GemBank;EMBL: AB017157 XR GemBank;EMBL: AK006429 XR GemBank;EMBL: AL844519 XR GemBank;EMBL: BC048486 XR CCDS: CCDS16850.1 XR RefSeq: NP_034109.1 XR STRING: 10090.ENSMUSP00000028935 XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR043250 XR InterPro: IPR000010 XR InterPro: IPR046350 XR PANTHER: PTHR46945 XR PROSITE: XR Ensembl: ENSGT00940000161877 XR KEGG: mmu:13013 XR GeneTree: ENSGT00940000161877 XR BRENDA: XR BioCyc: XR RNAct: Q9Z0H6 SQ SEQUENCE 16093.819 DA MW 137AA MSCPLRKKAL PLTMLLLLLS FHVLITPVSK ANKETNRSVH FIPTVEFAVN TFNQESQDEY AYRMEHIMSS WREKVNFPTV YSMRLQLRRT ICKKFEESLD ICPFQESHGL NNTFTCLFTV GTYPWITKFK LFRSVCS // ID AMPDB_4151 PN Cystatin-2 PF Cystatin-2 GN Not found SO Capra hircus (Goat) PL 15 PE Evidence at protein level XX AC 'A': 0, 'R': 0, 'N': 1, 'D': 3, 'C': 1, 'Q': 0, 'E': 1, 'G': 1, 'H': 1, 'I': 4, AC 'L': 0, 'K': 1, 'M': 0, 'F': 0, 'P': 0, 'S': 1, 'T': 1, 'W': 0, 'Y': 0, 'V': 0 AF 'A': 0%, 'R': 0%, 'N': 6.67%, 'D': 20%, 'C': 6.67%, 'Q': 0%, 'E': 6.67%, 'G': 6.67%, 'H': 6.67%, 'I': 26.67%, AF 'L': 0%, 'K': 6.67%, 'M': 0%, 'F': 0%, 'P': 0%, 'S': 6.67%, 'T': 6.67%, 'W': 0%, 'Y': 0%, 'V': 0% MA A, F, L, M, P, Q, R, V, W, Y MO I LO C, E, G, H, K, N, S, T BA 5 LA 10 AA 2 BC 4 MC 0 MF 0 XX MM 1672.827 AI 104 II 35.787 HP -0.4 HM 0.411 IP 4.061 C7 -2.97 SF 0.267, 0.2, 0.067 [Helix, Turn, Sheet] AR 0 ME 0, 0 XX TO S.aureus (Gram-positive) TO S.hemolyticus AM Antibiotic AM Antimicrobial AM Anti-gram-Positive EA Not found IE Protease inhibitor IE Thiol protease inhibitor OE Hemolytic OE Enzyme inhibitor OE Non-ribosomal XX XR PubMed: 16257555 XR UniProt: P84910 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P84910 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 1672.827 DA MW 15AA DTHISEKIID CNDIG // ID AMPDB_4152 PN Cystatin-1 PF Cystatin-1 GN Not found SO Capra hircus (Goat) PL 15 PE Evidence at protein level XX AC 'A': 0, 'R': 0, 'N': 1, 'D': 3, 'C': 1, 'Q': 0, 'E': 1, 'G': 1, 'H': 1, 'I': 4, AC 'L': 0, 'K': 1, 'M': 0, 'F': 0, 'P': 0, 'S': 1, 'T': 1, 'W': 0, 'Y': 0, 'V': 0 AF 'A': 0%, 'R': 0%, 'N': 6.67%, 'D': 20%, 'C': 6.67%, 'Q': 0%, 'E': 6.67%, 'G': 6.67%, 'H': 6.67%, 'I': 26.67%, AF 'L': 0%, 'K': 6.67%, 'M': 0%, 'F': 0%, 'P': 0%, 'S': 6.67%, 'T': 6.67%, 'W': 0%, 'Y': 0%, 'V': 0% MA A, F, L, M, P, Q, R, V, W, Y MO I LO C, E, G, H, K, N, S, T BA 5 LA 10 AA 2 BC 4 MC 0 MF 0 XX MM 1672.827 AI 104 II 35.787 HP -0.4 HM 0.411 IP 4.061 C7 -2.97 SF 0.267, 0.2, 0.067 [Helix, Turn, Sheet] AR 0 ME 0, 0 XX TO S.aureus (Gram-positive) TO S.hemolyticus AM Antibiotic AM Antimicrobial AM Anti-gram-Positive EA Not found IE Protease inhibitor IE Thiol protease inhibitor OE Hemolytic OE Enzyme inhibitor OE Non-ribosomal XX XR PubMed: 16257555 XR UniProt: P84911 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P84911 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 1672.827 DA MW 15AA DTHISEKIID CNDIG // ID AMPDB_4460 PN Cystatin-9 PF Cystatin-9 GN CST9 CLM CTES7A SO Homo sapiens (Human) PL 159 PE Evidence at transcript level XX AC 'A': 9, 'R': 11, 'N': 8, 'D': 8, 'C': 7, 'Q': 9, 'E': 10, 'G': 11, 'H': 2, 'I': 4, AC 'L': 15, 'K': 9, 'M': 9, 'F': 8, 'P': 6, 'S': 12, 'T': 5, 'W': 4, 'Y': 2, 'V': 10 AF 'A': 5.66%, 'R': 6.92%, 'N': 5.03%, 'D': 5.03%, 'C': 4.4%, 'Q': 5.66%, 'E': 6.29%, 'G': 6.92%, 'H': 1.26%, 'I': 2.52%, AF 'L': 9.43%, 'K': 5.66%, 'M': 5.66%, 'F': 5.03%, 'P': 3.77%, 'S': 7.55%, 'T': 3.14%, 'W': 2.52%, 'Y': 1.26%, 'V': 6.29% MA MO L LO H, Y BA 76 LA 83 AA 22 BC 18 MC 0 MF 0 XX MM 18134.919 AI 70.503 II 51.28 HP -0.356 HM 0.701 IP 8.042 C7 1.763 SF 0.27, 0.233, 0.27 [Helix, Turn, Sheet] AR 0.088 ME 24980, 25355 XX TO Francisella tularensis (Gram-negative) AM Antimicrobial AM Anti-gram-negative EA Not found IE Protease inhibitor IE Thiol protease inhibitor OE Enzyme inhibitor OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 12535658 XR PubMed: 11780052 XR PubMed: 15489334 XR PubMed: 20565543 XR PubMed: 23922243 XR UniProt: Q5W186 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q5W186 XR Genbank;EMBL: AF494536 XR Genbank;EMBL: AL121894 XR Genbank;EMBL: BC137302 XR Genbank;EMBL: BC137303 XR CCDS: CCDS33450.1 XR RefSeq: NP_001008693.2 XR STRING: 9606.ENSP00000366170 XR IntAct: Q5W186 XR MINT: XR DIP: XR BioGRID: 126160 XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR043250 XR InterPro: IPR046350 XR PANTHER: PTHR46945 XR PROSITE: XR Ensembl: ENSGT00940000164098 XR KEGG: hsa:128822 XR GeneTree: ENSGT00940000164098 XR BRENDA: XR BioCyc: XR RNAct: Q5W186 SQ SEQUENCE 18134.919 DA MW 159AA MSSPQRRKAM PWALSLLLMG FQLLVTYAWC SEEEMGGNNK IVQDPMFLAT VEFALNTFNV QSKEEHAYRL LRVLSSWRED SMDRKWRGKM VFSMNLQLRQ TVCRKFEDDI DNCPFQESLE LNNVRQGISF PQVHSCGCCM GCGVGTGAAD KAIPRDKGK // ID AMPDB_4528 PN L-cystatin PF L-cystatin GN Not found SO Tachypleus tridentatus (Japanese horseshoe crab) PL 133 PE Evidence at protein level XX AC 'A': 10, 'R': 5, 'N': 6, 'D': 4, 'C': 4, 'Q': 6, 'E': 9, 'G': 10, 'H': 4, 'I': 10, AC 'L': 10, 'K': 11, 'M': 2, 'F': 2, 'P': 4, 'S': 7, 'T': 9, 'W': 3, 'Y': 3, 'V': 14 AF 'A': 7.52%, 'R': 3.76%, 'N': 4.51%, 'D': 3.01%, 'C': 3.01%, 'Q': 4.51%, 'E': 6.77%, 'G': 7.52%, 'H': 3.01%, 'I': 7.52%, AF 'L': 7.52%, 'K': 8.27%, 'M': 1.5%, 'F': 1.5%, 'P': 3.01%, 'S': 5.26%, 'T': 6.77%, 'W': 2.26%, 'Y': 2.26%, 'V': 10.53% MA MO V LO F, M BA 65 LA 68 AA 20 BC 13 MC 0 MF 0 XX MM 14691.006 AI 96.692 II 35.546 HP -0.116 HM 0.675 IP 8.643 C7 3.126 SF 0.316, 0.203, 0.233 [Helix, Turn, Sheet] AR 0.06 ME 20970, 21220 XX TO Gram Negative Bacteria AM Antibiotic AM Antimicrobial AM Anti-gram-negative EA Not found IE Protease inhibitor IE Thiol protease inhibitor OE Enzyme inhibitor OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 8907180 XR UniProt: Q7M429 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q7M429 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR000010 XR InterPro: IPR046350 XR InterPro: IPR018073 XR PANTHER: XR PROSITE: PS00287 XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 14691.006 DA MW 133AA MEGYNILAVL IILVGVSMGQ IPGGWIDANV GDTDVKEAAR FATEAQSSRS NSLYHHKLLK IHKARTQVVS GINYEVFIET GTTTCKKSEV PLEDLKRCAV PENGVKHLCQ AIVWVQAWIP RTKVTKLECQ NKG //